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Germline HSD3B1 Genetics and Prostate Cancer Outcomes
Dihydrotestosterone synthesis in prostate cancer from adrenal DHEA/DHEA-sulfate requires enzymatic conversion in tumor tissues. 3β-hydroxysteroid dehydrogenase-1 (3β-HSD1) is an absolutely necessary enzyme for such dihydrotestosterone synthesis and is encoded by the gene HSD3B1 which comes in two fu...
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| Publicado no: | Urology |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7657962/ https://ncbi.nlm.nih.gov/pubmed/32866512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urology.2020.08.028 |
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