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Germline PTEN mutations are associated with a skewed peripheral immune repertoire in humans and mice
Individuals with germline mutations in the gene encoding phosphatase and tensin homolog on chromosome ten (PTEN) are diagnosed with PTEN hamartoma tumor syndrome (PHTS) and are at high risk for developing breast, thyroid and other cancers and/or autoimmunity or neurodevelopmental issues including au...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7424751/ https://ncbi.nlm.nih.gov/pubmed/32588888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa118 |
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