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Dynamics and Structural Stability Effects of Germline PTEN Mutations Associated with Cancer versus Autism Phenotypes

Individuals with germline mutations in the tumor suppressor gene phosphatase and tensin homolog (PTEN), irrespective of clinical presentation, are diagnosed with PTEN hamartoma tumor syndrome (PHTS). PHTS confers a high risk of breast, thyroid, and other cancers or autism spectrum disorder (ASD) wit...

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Pubblicato in:J Biomol Struct Dyn
Autori principali: Smith, Iris Nira, Thacker, Stetson, Jaini, Ritika, Eng, Charis
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235728/
https://ncbi.nlm.nih.gov/pubmed/29663862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2018.1465854
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