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Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders

The blood-brain barrier (BBB) allows the brain to selectively import nutrients and energy critical to neuronal function while simultaneously excluding neurotoxic substances from the peripheral circulation. In contrast to the highly permeable vasculature present in most organs that reside outside of...

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Détails bibliographiques
Publié dans:Front Physiol
Auteurs principaux: Lochhead, Jeffrey J., Yang, Junzhi, Ronaldson, Patrick T., Davis, Thomas P.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424030/
https://ncbi.nlm.nih.gov/pubmed/32848858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00914
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