Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System

Por Lochhead, Jeffrey J., Ronaldson, Patrick T., Davis, Thomas P.
Publicado no AAPS J (2017)

Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration

Por Lochhead, Jeffrey J, Wolak, Daniel J, Pizzo, Michelle E, Thorne, Robert G
Publicado no J Cereb Blood Flow Metab (2015)

Relative vascular permeability and vascularity across different regions of the rat nasal mucosa: implications for nasal physiology and drug delivery

Por Kumar, Niyanta N., Gautam, Mohan, Lochhead, Jeffrey J., Wolak, Daniel J., Ithapu, Vamsi, Singh, Vikas, Thorne, Robert G.
Publicado no Sci Rep (2016)

Oxidative stress increases blood–brain barrier permeability and induces alterations in occludin during hypoxia–reoxygenation

Por Lochhead, Jeffrey J, McCaffrey, Gwen, Quigley, Colleen E, Finch, Jessica, DeMarco, Kristin M, Nametz, Nicole, Davis, Thomas P
Publicado em 2010

Oxidative stress increases blood–brain barrier permeability and induces alterations in occludin during hypoxia–reoxygenation

Por Lochhead, Jeffrey J, McCaffrey, Gwen, Quigley, Colleen E, Finch, Jessica, DeMarco, Kristin M, Nametz, Nicole, Davis, Thomas P
Publicado em 2011

Occludin oligomeric assemblies at tight junctions of the blood–brain barrier are altered by hypoxia and reoxygenation stress

Por McCaffrey, Gwen, Willis, Colin L., Staatz, William D., Nametz, Nicole, Quigley, Carolyn A., Hom, Sharon, Lochhead, Jeffrey J., Davis, Thomas P.
Publicado em 2009

Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain

Por Lochhead, Jeffrey J., McCaffrey, Gwen, Sanchez-Covarrubias, Lucy, Finch, Jessica D., DeMarco, Kristin M., Quigley, Colleen E., Davis, Thomas P., Ronaldson, Patrick T.
Publicado em 2012