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Occludin oligomeric assemblies at tight junctions of the blood–brain barrier are altered by hypoxia and reoxygenation stress

Hypoxic (low oxygen) and reperfusion (post-hypoxic reoxygenation) phases of stroke promote an increase in microvascular permeability at tight junctions (TJs) of the blood–brain barrier (BBB) that may lead to cerebral edema. To investigate the effect of hypoxia (Hx) and reoxygenation on oligomeric as...

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Detalhes bibliográficos
Main Authors: McCaffrey, Gwen, Willis, Colin L., Staatz, William D., Nametz, Nicole, Quigley, Carolyn A., Hom, Sharon, Lochhead, Jeffrey J., Davis, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313603/
https://ncbi.nlm.nih.gov/pubmed/19457074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06113.x
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