Oxidative stress increases blood–brain barrier permeability and induces alterations in occludin during hypoxia–reoxygenation

The blood–brain barrier (BBB) has a critical role in central nervous system homeostasis. Intercellular tight junction (TJ) protein complexes of the brain microvasculature limit paracellular diffusion of substances from the blood into the brain. Hypoxia and reoxygenation (HR) is a central component t...

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Main Authors: Lochhead, Jeffrey J, McCaffrey, Gwen, Quigley, Colleen E, Finch, Jessica, DeMarco, Kristin M, Nametz, Nicole, Davis, Thomas P
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949263/
https://ncbi.nlm.nih.gov/pubmed/20234382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.29
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