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Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration
The intranasal administration route is increasingly being used as a noninvasive method to bypass the blood–brain barrier because evidence suggests small fractions of nasally applied macromolecules may reach the brain directly via olfactory and trigeminal nerve components present in the nasal mucosa....
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| Publicado no: | J Cereb Blood Flow Metab |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4348383/ https://ncbi.nlm.nih.gov/pubmed/25492117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.215 |
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