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Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose-response, and mechanisms of delivery

The intranasal route has been hypothesized to circumvent the blood-brain and blood-cerebrospinal fluid barriers, allowing entry into the brain via extracellular pathways along olfactory and trigeminal nerves and the perivascular spaces (PVS) of cerebral blood vessels. We investigated the potential o...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Control Release
Päätekijät: Kumar, Niyanta N., Lochhead, Jeffrey J., Pizzo, Michelle E., Nehra, Geetika, Boroumand, Sam, Greene, Gretchen, Thorne, Robert G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7234798/
https://ncbi.nlm.nih.gov/pubmed/30081144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.08.006
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