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Intranasal administration of elastin-like polypeptide for therapeutic delivery to the central nervous system

Bypassing the blood–brain barrier is one of the primary considerations when designing compounds intended to function in the central nervous system (CNS). Intranasal (IN) administration of otherwise blood–brain barrier impermeable molecules can result in high CNS concentrations and low systemic accum...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: McGowan, Jeremy WD, Shao, Qingmei, Vig, Parminder JS, Bidwell, Gene L
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019317/
https://ncbi.nlm.nih.gov/pubmed/27660412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S106216
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