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Intranasal administration of elastin-like polypeptide for therapeutic delivery to the central nervous system

Bypassing the blood–brain barrier is one of the primary considerations when designing compounds intended to function in the central nervous system (CNS). Intranasal (IN) administration of otherwise blood–brain barrier impermeable molecules can result in high CNS concentrations and low systemic accum...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: McGowan, Jeremy WD, Shao, Qingmei, Vig, Parminder JS, Bidwell, Gene L
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019317/
https://ncbi.nlm.nih.gov/pubmed/27660412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S106216
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