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Intranasal administration of elastin-like polypeptide for therapeutic delivery to the central nervous system

Bypassing the blood–brain barrier is one of the primary considerations when designing compounds intended to function in the central nervous system (CNS). Intranasal (IN) administration of otherwise blood–brain barrier impermeable molecules can result in high CNS concentrations and low systemic accum...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Drug Des Devel Ther
Prif Awduron: McGowan, Jeremy WD, Shao, Qingmei, Vig, Parminder JS, Bidwell, Gene L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019317/
https://ncbi.nlm.nih.gov/pubmed/27660412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S106216
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