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Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection

The blood-brain barrier (BBB) is a physical and biochemical barrier that precisely controls cerebral homeostasis. It also plays a central role in the regulation of blood-to-brain flux of endogenous and exogenous xenobiotics and associated metabolites. This is accomplished by molecular characteristic...

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Bibliographic Details
Published in:Am J Physiol Cell Physiol
Main Authors: Abdullahi, Wazir, Tripathi, Dinesh, Ronaldson, Patrick T.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171039/
https://ncbi.nlm.nih.gov/pubmed/29949404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00095.2018
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