Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders

The blood-brain barrier (BBB) allows the brain to selectively import nutrients and energy critical to neuronal function while simultaneously excluding neurotoxic substances from the peripheral circulation. In contrast to the highly permeable vasculature present in most organs that reside outside of...

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Veröffentlicht in:Front Physiol
Hauptverfasser: Lochhead, Jeffrey J., Yang, Junzhi, Ronaldson, Patrick T., Davis, Thomas P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424030/
https://ncbi.nlm.nih.gov/pubmed/32848858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00914
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