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Synthesis of Tetrahydroisoquinolines Through an Iron-Catalyzed Cascade: Tandem Alcohol Substitution and Hydroamination

Rapid assembly of saturated nitrogen hetero-cycles—the synthetically more challenging variants of their aromatic relatives—can expedite the synthesis of biologically relevant molecules. Starting from a benzylic alcohol tethered to an unactivated alkene, an iron-catalyzed tandem alcohol substitution...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Org Lett
Main Authors: Marcyk, Paul T., Cook, Silas P.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423316/
https://ncbi.nlm.nih.gov/pubmed/31418575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b02353
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