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Asymmetric Synthesis of γ-Amino Alcohols by Copper-Catalyzed Hydroamination

Asymmetric synthesis of γ-amino alcohols from unprotected allylic alcohols by a copper-catalyzed hydroamination strategy has been developed. Using easily accessible starting materials, a range of chiral 1,3-amino alcohols were prepared with excellent regio- and enantioselectivity. Further, this prot...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Org Lett
Hauptverfasser: Ichikawa, Saki, Buchwald, Stephen L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956864/
https://ncbi.nlm.nih.gov/pubmed/31625750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b03356
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