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CuH-Catalyzed Regioselective Intramolecular Hydroamination for the Synthesis of Alkyl-Substituted Chiral Aziridines

This report details a general and enantioselective means for the synthesis of alkyl-substituted aziridines. This protocol offers a direct route for the synthesis of alkyl-substituted chiral aziridines from achiral starting materials. Readily accessed allylic hydroxylamine esters undergo copper hydri...

詳細記述

保存先:
書誌詳細
出版年:J Am Chem Soc
主要な著者: Wang, Haoxuan, Yang, Jeffrey C., Buchwald, Stephen L.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656387/
https://ncbi.nlm.nih.gov/pubmed/28594548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b04816
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