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Synthesis of Tetrahydroisoquinolines Through an Iron-Catalyzed Cascade: Tandem Alcohol Substitution and Hydroamination
Rapid assembly of saturated nitrogen hetero-cycles—the synthetically more challenging variants of their aromatic relatives—can expedite the synthesis of biologically relevant molecules. Starting from a benzylic alcohol tethered to an unactivated alkene, an iron-catalyzed tandem alcohol substitution...
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| Publicado en: | Org Lett |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7423316/ https://ncbi.nlm.nih.gov/pubmed/31418575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b02353 |
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