SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis

Human immunodeficiency virus infection is the most common risk factor for severe forms of tuberculosis (TB), regardless of CD4 T cell count. Using a well-characterized cynomolgus macaque model of human TB, we compared radiographic, immunologic and microbiologic characteristics of early (subclinical)...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Diedrich, Collin R., Rutledge, Tara, Maiello, Pauline, Baranowski, Tonilynn M., White, Alexander G., Borish, H. Jacob, Karell, Paul, Hopkins, Forrest, Brown, Jessica, Fortune, Sarah M., Flynn, JoAnne L., Ambrose, Zandrea, Lin, Philana Ling
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419014/
https://ncbi.nlm.nih.gov/pubmed/32730321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008413
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