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SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis

Human immunodeficiency virus infection is the most common risk factor for severe forms of tuberculosis (TB), regardless of CD4 T cell count. Using a well-characterized cynomolgus macaque model of human TB, we compared radiographic, immunologic and microbiologic characteristics of early (subclinical)...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Diedrich, Collin R., Rutledge, Tara, Maiello, Pauline, Baranowski, Tonilynn M., White, Alexander G., Borish, H. Jacob, Karell, Paul, Hopkins, Forrest, Brown, Jessica, Fortune, Sarah M., Flynn, JoAnne L., Ambrose, Zandrea, Lin, Philana Ling
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419014/
https://ncbi.nlm.nih.gov/pubmed/32730321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008413
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