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Monocyte-Derived IL-5 Reduces TNF Production by Mycobacterium tuberculosis–specific CD4 T Cells during SIV/M. tuberculosis Coinfection

HIV-infected individuals are significantly more susceptible to tuberculosis (TB) than uninfected individuals. Although it is established that HIV reduces Mycobacterium tuberculosis–specific T cell responses, the causes of this dysfunction are not known. We used the cynomolgus macaque model of TB to...

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Detalhes bibliográficos
Main Authors: Diedrich, Collin R., Mattila, Joshua T., Flynn, JoAnne L.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677169/
https://ncbi.nlm.nih.gov/pubmed/23690470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202043
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