Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization

Lung granulomas are the pathologic hallmark of tuberculosis (TB). T cells are a major cellular component of TB lung granulomas and are known to play an important role in containment of Mycobacterium tuberculosis (Mtb) infection. We used cynomolgus macaques, a non-human primate model that recapitulat...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Gideon, Hannah Priyadarshini, Phuah, JiaYao, Myers, Amy J., Bryson, Bryan D., Rodgers, Mark A., Coleman, M. Teresa, Maiello, Pauline, Rutledge, Tara, Marino, Simeone, Fortune, Sarah M., Kirschner, Denise E., Lin, Philana Ling, Flynn, JoAnne L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303275/
https://ncbi.nlm.nih.gov/pubmed/25611466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004603
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker