Bmi deficiency causes oxidative stress and intervertebral disc degeneration which can be alleviated by antioxidant treatment

The transcriptional repressor Bmi‐1 is involved in cell‐cycle regulation and cell senescence, the deficiency of which has been shown to cause oxidative stress. This study investigated whether Bmi‐1 deficiency plays a role in promoting disc degeneration and the effect of treatment with antioxidant N‐...

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Publicat a:J Cell Mol Med
Autors principals: Zhang, Qunhu, Li, Jie, Li, You, Che, Hui, Chen, Ying, Dong, Jianghui, Xian, Cory J., Miao, Dengshun, Wang, Liping, Ren, Yongxin
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417700/
https://ncbi.nlm.nih.gov/pubmed/32583517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15528
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