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Estradiol Alleviates Intervertebral Disc Degeneration through Modulating the Antioxidant Enzymes and Inhibiting Autophagy in the Model of Menopause Rats

OBJECTIVE: To investigate the effects of menopause on redox balance in the intervertebral disc and to examine whether oxidative stress and autophagy were associated with disc degeneration in menopause rats. METHODS: Thirty female Sprague-Dawley rats were randomly divided into three groups (sham, ova...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Jin, Lin-Yu, Lv, Zhen-Dong, Wang, Kun, Qian, Lie, Song, Xiao-Xing, Li, Xin-Feng, Shen, Hong-Xing
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323532/
https://ncbi.nlm.nih.gov/pubmed/30671175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7890291
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