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Targeting Piezo1 channel to alleviate intervertebral disc degeneration

Background: Low back pain impacts over 600 million people worldwide, predominantly due to intervertebral disc degeneration. This study focuses on the role of Piezo1, a crucial mechanosensitive ion channel protein, in the pathology and potential treatment of disc degeneration. Materials and methods:...

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Principais autores: Feiyun Li, Mingjue Chen, Mengrui Zhang, Sheng Chen, Minghao Qu, Shuangshuang He, Lin Wang, Xiaohao Wu, Guozhi Xiao
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2025-03-01
Serija:Journal of Orthopaedic Translation
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Online dostop:http://www.sciencedirect.com/science/article/pii/S2214031X25000075
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