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Bmi deficiency causes oxidative stress and intervertebral disc degeneration which can be alleviated by antioxidant treatment

The transcriptional repressor Bmi‐1 is involved in cell‐cycle regulation and cell senescence, the deficiency of which has been shown to cause oxidative stress. This study investigated whether Bmi‐1 deficiency plays a role in promoting disc degeneration and the effect of treatment with antioxidant N‐...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhang, Qunhu, Li, Jie, Li, You, Che, Hui, Chen, Ying, Dong, Jianghui, Xian, Cory J., Miao, Dengshun, Wang, Liping, Ren, Yongxin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417700/
https://ncbi.nlm.nih.gov/pubmed/32583517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15528
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