Mammalian SWI/SNF complex genomic alterations and immune checkpoint blockade in solid tumors

Prior data have variably implicated the inactivation of the mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) complex with increased tumor sensitivity to immune checkpoint inhibitors (ICIs). Herein, we examined the association between mSWI/SNF variants and clinical outcomes to ICIs. We correlated...

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Библиографические подробности
Опубликовано в: :Cancer Immunol Res
Главные авторы: Alaiwi, Sarah Abou, Nassar, Amin H., Xie, Wanling, Bakouny, Ziad, Berchuck, Jacob E., Braun, David A., Baca, Sylvan C., Nuzzo, Pier Vitale, Flippot, Ronan, Mouhieddine, Tarek H., Spurr, Liam F., Li, Yvonne Y., Li, Taiwen, Flaifel, Abdallah, Steinharter, John A., Margolis, Claire A., Vokes, Natalie I., Du, Heng, Shukla, Sachet A., Cherniack, Andrew D., Sonpavde, Guru, Haddad, Robert I., Awad, Mark M., Giannakis, Marios, Hodi, F. Stephen, Liu, X. Shirley, Signoretti, Sabina, Kadoch, Cigall, Freedman, Matthew L., Kwiatkowski, David J., Van Allen, Eliezer, Choueiri, Toni K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415546/
https://ncbi.nlm.nih.gov/pubmed/32321774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0866
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