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Reversible Disruption of mSWI/SNF (BAF) Complexes by the SS18-SSX Oncogenic Fusion in Synovial Sarcoma
Recent exon sequencing studies have revealed that over 19% of human tumors have mutations in subunits of mSWI/SNF (BAF) complexes. To investigate the underlying mechanism we studied human synovial sarcoma (SS), in which transformation results from the translocation of exactly 78 amino acids of SSX t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3655887/ https://ncbi.nlm.nih.gov/pubmed/23540691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.02.036 |
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