Proteomic and Bioinformatic Analysis of mSWI/SNF (BAF) Complexes Reveals Extensive Roles in Human Malignancy

Subunits of mammalian SWI/SNF (mSWI/SNF, also called BAF) complexes have recently been implicated as tumor suppressors in a number of human malignancies. To understand the full extent of their involvement, we conducted a proteomic analysis of purified endogenous mSWI/SNF complexes. Our studies revea...

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Bibliografiske detaljer
Main Authors: Kadoch, Cigall, Hargreaves, Diana C., Hodges, Courtney, Elias, Laura, Ho, Lena, Ranish, Jeff, Crabtree, Gerald R.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667980/
https://ncbi.nlm.nih.gov/pubmed/23644491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2628
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