Mammalian SWI/SNF complex genomic alterations and immune checkpoint blockade in solid tumors

Prior data have variably implicated the inactivation of the mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) complex with increased tumor sensitivity to immune checkpoint inhibitors (ICIs). Herein, we examined the association between mSWI/SNF variants and clinical outcomes to ICIs. We correlated...

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Bibliografiset tiedot
Julkaisussa:Cancer Immunol Res
Päätekijät: Alaiwi, Sarah Abou, Nassar, Amin H., Xie, Wanling, Bakouny, Ziad, Berchuck, Jacob E., Braun, David A., Baca, Sylvan C., Nuzzo, Pier Vitale, Flippot, Ronan, Mouhieddine, Tarek H., Spurr, Liam F., Li, Yvonne Y., Li, Taiwen, Flaifel, Abdallah, Steinharter, John A., Margolis, Claire A., Vokes, Natalie I., Du, Heng, Shukla, Sachet A., Cherniack, Andrew D., Sonpavde, Guru, Haddad, Robert I., Awad, Mark M., Giannakis, Marios, Hodi, F. Stephen, Liu, X. Shirley, Signoretti, Sabina, Kadoch, Cigall, Freedman, Matthew L., Kwiatkowski, David J., Van Allen, Eliezer, Choueiri, Toni K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415546/
https://ncbi.nlm.nih.gov/pubmed/32321774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0866
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