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Disruption of mammalian SWI/SNF and polycomb complexes in human sarcomas: mechanisms and therapeutic opportunities

Soft-tissue sarcomas are increasingly characterized and subclassified by genetic abnormalities that represent underlying drivers of their pathology. Hallmark tumor suppressor gene mutations and pathognomonic gene fusions collectively account for approximately one-third of all sarcomas. These genetic...

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Publicado en:J Pathol
Main Authors: McBride, Matthew J, Kadoch, Cigall
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755911/
https://ncbi.nlm.nih.gov/pubmed/29359803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5042
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