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Two-stage optimal designs based on exact variance for a single-arm trial with survival endpoints
Sample size calculation based on normal approximations is often associated with the loss of statistical power for a single-arm trial with time-to-event endpoint. Recently, Wu (2015) derived the exact variance for the one-sample log-rank test under the alternative, and showed that a single-arm one-st...
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| Udgivet i: | J Biopharm Stat |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7415526/ https://ncbi.nlm.nih.gov/pubmed/32129130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2020.1730869 |
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