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Efficient confidence limits for adaptive one-arm two-stage clinical trials with binary endpoints

BACKGROUND: Recently, several adaptive one-arm two-stage designs have been developed by fully using the information from previous stages to reduce the expected sample size in clinical trials with binary endpoints as primary outcome. It is important to compute exact confidence limits for these studie...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:BMC Med Res Methodol
मुख्य लेखकों: Shan, Guogen, Zhang, Hua, Jiang, Tao
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294881/
https://ncbi.nlm.nih.gov/pubmed/28166741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-017-0297-5
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