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The third model of Bax/Bak activation: a Bcl-2 family feud finally resolved?

Bax and Bak, two functionally similar, pro-apoptotic proteins of the Bcl-2 family, are known as the gateway to apoptosis because of their requisite roles as effectors of mitochondrial outer membrane permeabilization (MOMP), a major step during mitochondria-dependent apoptosis. The mechanism of how c...

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Pubblicato in:F1000Res
Autori principali: Luo, Xu, O'Neill, Katelyn L., Huang, Kai
Natura: Artigo
Lingua:Inglês
Pubblicazione: F1000 Research Limited 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411521/
https://ncbi.nlm.nih.gov/pubmed/32802314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.25607.1
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