Novel formyl peptide receptor (FPR) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis

The resolution of inflammation is an active response involving the interaction of pro-resolving mediators with specific receptors, such as N-formyl peptide receptor 2 (FPR2). FPRs represent potentially important therapeutic targets for the treatment of some pathologies, including asthma and rheumato...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioorg Chem
Prif Awduron: Crocetti, Letizia, Vergelli, Claudia, Guerrini, Gabriella, Cantini, Niccolò, Kirpotina, Liliya N., Schepetkin, Igor A., Quinn, Mark T., Parisio, Carmen, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Giovannoni, Maria Paola
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409366/
https://ncbi.nlm.nih.gov/pubmed/32388428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2020.103880
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