Synthesis of five and six-membered N-phenylacetamido substituted heterocycles as formyl peptide receptor (FPR) agonists

Formyl peptide receptors (FPRs) are G-protein-coupled receptors that play an important role in the regulation of inflammatory process and cellular dysfunction. In humans, three different isoforms are expressed (FPR1, FPR2 and FPR3). FPR2 appears to be directly involved in the resolution of inflammat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Drug Dev Res
Prif Awduron: Vergelli, Claudia, Schepetkin, Igor A., Ciciani, Giovanna, Cilibrizzi, Agostino, Crocetti, Letizia, Giovannoni, Maria Paola, Guerrini, Gabriella, Iacovone, Antonella, Kirpotina, Liliya N., Ye, Richard D., Quinn, Mark T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299035/
https://ncbi.nlm.nih.gov/pubmed/27859446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ddr.21370
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