Novel formyl peptide receptor (FPR) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis

The resolution of inflammation is an active response involving the interaction of pro-resolving mediators with specific receptors, such as N-formyl peptide receptor 2 (FPR2). FPRs represent potentially important therapeutic targets for the treatment of some pathologies, including asthma and rheumato...

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Publicado en:Bioorg Chem
Main Authors: Crocetti, Letizia, Vergelli, Claudia, Guerrini, Gabriella, Cantini, Niccolò, Kirpotina, Liliya N., Schepetkin, Igor A., Quinn, Mark T., Parisio, Carmen, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Giovannoni, Maria Paola
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409366/
https://ncbi.nlm.nih.gov/pubmed/32388428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2020.103880
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