Antagonism of Human Formyl Peptide Receptor 1 (FPR1) by Chromones and Related Isoflavones

Formyl peptide receptors (FPRs) are G protein-coupled receptors (GPCRs) expressed on a variety of cell types. Because FPRs play an important role in the regulation of inflammatory reactions implicated in disease pathogenesis, FPR antagonists may represent novel therapeutics for modulating innate imm...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Schepetkin, Igor A., Kirpotina, Liliya N., Khlebnikov, Andrei I., Cheng, Ni, Ye, Richard D., Quinn, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314359/
https://ncbi.nlm.nih.gov/pubmed/25450672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.09.027
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