3-(1H-Indol-3-yl)-2-[3-(4-nitrophenyl)ureido]propanamide Enantiomers With Human Formyl-Peptide Receptor Agonist Activity: Molecular Modeling of Chiral Recognition by FPR2

N-formyl peptide receptors (FPRs) are G protein-coupled receptors (GPCRs) that play critical roles in inflammatory reactions, and FPR-specific interactions can possibly be used to facilitate the resolution of pathological inflammatory reactions. Recent studies indicated that FPRs have stereo-selecti...

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Detalhes bibliográficos
Main Authors: Schepetkin, Igor A., Kirpotina, Liliya N., Khlebnikov, Andrei I., Leopoldo, Marcello, Lucente, Ermelinda, Lacivita, Enza, De Giorgio, Paola, Quinn, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553303/
https://ncbi.nlm.nih.gov/pubmed/23219934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.11.015
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