Synthetic DNA Delivery of an Engineered Arginase Enzyme Can Modulate Specific Immunity In Vivo

Arginase is a complex and unique enzyme that plays diverse roles in health and disease. By metabolizing arginine, it can shape the outcome of innate and adaptive immune responses. The immunomodulatory capabilities of arginase could potentially be applied for local immunosuppression or induction of i...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Khoshnejad, Makan, Perales-Puchalt, Alfredo, Dia, Yaya, Xiao, Peng, Patel, Ami, Xu, Ziyang, Zhu, Xizhou, Yun, Kun, Baboo, Ishana, Qureshi, Rehman, Humeau, Laurent, Muthumani, Kar, Weiner, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406982/
https://ncbi.nlm.nih.gov/pubmed/32802913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.05.025
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