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The Polycomb-associated factor PHF19 controls hematopoietic stem cell state and differentiation

Adult hematopoietic stem cells (HSCs) are rare multipotent cells in bone marrow that are responsible for generating all blood cell types. HSCs are a heterogeneous group of cells with high plasticity, in part, conferred by epigenetic mechanisms. PHF19, a subunit of the Polycomb repressive complex 2 (...

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Pubblicato in:Sci Adv
Autori principali: Vizán, Pedro, Gutiérrez, Arantxa, Espejo, Isabel, García-Montolio, Marc, Lange, Martin, Carretero, Ana, Lafzi, Atefeh, de Andrés-Aguayo, Luisa, Blanco, Enrique, Thambyrajah, Roshana, Graf, Thomas, Heyn, Holger, Bigas, Anna, Di Croce, Luciano
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406347/
https://ncbi.nlm.nih.gov/pubmed/32821835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb2745
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