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PHF19 mediated regulation of proliferation and invasiveness in prostate cancer cells

The Polycomb-like protein PHF19/PCL3 associates with PRC2 and mediates its recruitment to chromatin in embryonic stem cells. PHF19 is also overexpressed in many cancers. However, neither PHF19 targets nor misregulated pathways involving PHF19 are known. Here, we investigate the role of PHF19 in pros...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Jain, Payal, Ballare, Cecilia, Blanco, Enrique, Vizan, Pedro, Di Croce, Luciano
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064337/
https://ncbi.nlm.nih.gov/pubmed/32155117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51373
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