Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity

Polycomb-group proteins are transcriptional repressors with essential roles in embryonic development. Polycomb repressive complex 2 (PRC2) contains the methyltransferase activity for Lys27. However, the role of other histone modifications in regulating PRC2 activity is just beginning to be understoo...

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Huvudupphovsmän: Ballaré, Cecilia, Lange, Martin, Lapinaite, Audrone, Martin, Gloria Mas, Morey, Lluis, Pascual, Gloria, Liefke, Robert, Simon, Bernd, Shi, Yang, Gozani, Or, Carlomagno, Teresa, Benitah, Salvador Aznar, Croce, Luciano Di
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926938/
https://ncbi.nlm.nih.gov/pubmed/23104054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2434
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