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Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity
Polycomb-group proteins are transcriptional repressors with essential roles in embryonic development. Polycomb repressive complex 2 (PRC2) contains the methyltransferase activity for Lys27. However, the role of other histone modifications in regulating PRC2 activity is just beginning to be understoo...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3926938/ https://ncbi.nlm.nih.gov/pubmed/23104054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2434 |
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