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The Polycomb-associated factor PHF19 controls hematopoietic stem cell state and differentiation

Adult hematopoietic stem cells (HSCs) are rare multipotent cells in bone marrow that are responsible for generating all blood cell types. HSCs are a heterogeneous group of cells with high plasticity, in part, conferred by epigenetic mechanisms. PHF19, a subunit of the Polycomb repressive complex 2 (...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Vizán, Pedro, Gutiérrez, Arantxa, Espejo, Isabel, García-Montolio, Marc, Lange, Martin, Carretero, Ana, Lafzi, Atefeh, de Andrés-Aguayo, Luisa, Blanco, Enrique, Thambyrajah, Roshana, Graf, Thomas, Heyn, Holger, Bigas, Anna, Di Croce, Luciano
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406347/
https://ncbi.nlm.nih.gov/pubmed/32821835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb2745
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