The Polycomb-associated factor PHF19 controls hematopoietic stem cell state and differentiation

Adult hematopoietic stem cells (HSCs) are rare multipotent cells in bone marrow that are responsible for generating all blood cell types. HSCs are a heterogeneous group of cells with high plasticity, in part, conferred by epigenetic mechanisms. PHF19, a subunit of the Polycomb repressive complex 2 (...

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Библиографические подробности
Опубликовано в: :Sci Adv
Главные авторы: Vizán, Pedro, Gutiérrez, Arantxa, Espejo, Isabel, García-Montolio, Marc, Lange, Martin, Carretero, Ana, Lafzi, Atefeh, de Andrés-Aguayo, Luisa, Blanco, Enrique, Thambyrajah, Roshana, Graf, Thomas, Heyn, Holger, Bigas, Anna, Di Croce, Luciano
Формат: Artigo
Язык:Inglês
Опубликовано: American Association for the Advancement of Science 2020
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406347/
https://ncbi.nlm.nih.gov/pubmed/32821835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb2745
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