Deletion of Calcineurin in Schwann Cells Does Not Affect Developmental Myelination, But Reduces Autophagy and Delays Myelin Clearance after Peripheral Nerve Injury

In the PNS, myelination occurs postnatally when Schwann cells (SCs) contact axons. Axonal factors, such as Neuregulin-1 Type III, trigger promyelinating signals that upregulate myelin genes. Neuregulin-1 Type III has been proposed to activate calcineurin signaling in immature SCs to initiate differe...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Reed, Chelsey B., Frick, Luciana R., Weaver, Adam, Sidoli, Mariapaola, Schlant, Elizabeth, Feltri, M. Laura, Wrabetz, Lawrence
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2020
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406276/
https://ncbi.nlm.nih.gov/pubmed/32641402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0951-20.2020
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares