Inter-Regulation of K(v)4.3 and Voltage-Gated Sodium Channels Underlies Predisposition to Cardiac and Neuronal Channelopathies

Background: Genetic variants in voltage-gated sodium channels (Na(v)) encoded by SCNXA genes, responsible for I(Na), and K(v)4.3 channels encoded by KCND3, responsible for the transient outward current (I(to)), contribute to the manifestation of both Brugada syndrome (BrS) and spinocerebellar ataxia...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Clatot, Jérôme, Neyroud, Nathalie, Cox, Robert, Souil, Charlotte, Huang, Jing, Guicheney, Pascale, Antzelevitch, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404392/
https://ncbi.nlm.nih.gov/pubmed/32709127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21145057
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