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Voltage-Gated Sodium Channels: Biophysics, Pharmacology, and Related Channelopathies

Voltage-gated sodium channels (VGSC) are multi-molecular protein complexes expressed in both excitable and non-excitable cells. They are primarily formed by a pore-forming multi-spanning integral membrane glycoprotein (α-subunit) that can be associated with one or more regulatory β-subunits. The lat...

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Main Authors: Savio-Galimberti, Eleonora, Gollob, Michael H., Darbar, Dawood
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Research Foundation 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394224/
https://ncbi.nlm.nih.gov/pubmed/22798951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00124
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