Voltage-gated sodium channels assemble and gate as dimers

Fast opening and closing of voltage-gated sodium channels are crucial for proper propagation of the action potential through excitable tissues. Unlike potassium channels, sodium channel α-subunits are believed to form functional monomers. Yet, an increasing body of literature shows inconsistency wit...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Clatot, Jérôme, Hoshi, Malcolm, Wan, Xiaoping, Liu, Haiyan, Jain, Ankur, Shinlapawittayatorn, Krekwit, Marionneau, Céline, Ficker, Eckhard, Ha, Taekjip, Deschênes, Isabelle
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727259/
https://ncbi.nlm.nih.gov/pubmed/29233994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02262-0
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