Interferon-stimulated gene 15 accelerates replication fork progression inducing chromosomal breakage

DNA replication is highly regulated by the ubiquitin system, which plays key roles upon stress. The ubiquitin-like modifier ISG15 (interferon-stimulated gene 15) is induced by interferons, bacterial and viral infection, and DNA damage, but it is also constitutively expressed in many types of cancer,...

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Publicat a:J Cell Biol
Autors principals: Raso, Maria Chiara, Djoric, Nikola, Walser, Franziska, Hess, Sandra, Schmid, Fabian Marc, Burger, Sibylle, Knobeloch, Klaus-Peter, Penengo, Lorenza
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401800/
https://ncbi.nlm.nih.gov/pubmed/32597933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202002175
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