Mus81 and converging forks limit the mutagenicity of replication fork breakage

Most spontaneous DNA double-strand breaks (DSBs) result from replication-fork breakage. Break-induced replication (BIR), a genome rearrangement-prone repair mechanism that requires the Pol32/POLD3 subunit of eukaryotic DNA Polδ, was proposed to repair broken forks, but how genome destabilization is...

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Detaylı Bibliyografya
Yayımlandı:Science
Asıl Yazarlar: Mayle, Ryan, Campbell, Ian M., Beck, Christine R., Yu, Yang, Wilson, Marenda, Shaw, Chad A., Bjergbaek, Lotte, Lupski, James R., Ira, Grzegorz
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782627/
https://ncbi.nlm.nih.gov/pubmed/26273056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa8391
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