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Interferon-stimulated gene 15 accelerates replication fork progression inducing chromosomal breakage
DNA replication is highly regulated by the ubiquitin system, which plays key roles upon stress. The ubiquitin-like modifier ISG15 (interferon-stimulated gene 15) is induced by interferons, bacterial and viral infection, and DNA damage, but it is also constitutively expressed in many types of cancer,...
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Publicado en: | J Cell Biol |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
Rockefeller University Press
2020
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7401800/ https://ncbi.nlm.nih.gov/pubmed/32597933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202002175 |
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