Dorsoventral polarity directs cell responses to migration track geometries

How migrating cells differentially adapt and respond to extracellular track geometries remains unknown. Using intravital imaging, we demonstrate that invading cells exhibit dorsoventral (top-to-bottom) polarity in vivo. To investigate the impact of dorsoventral polarity on cell locomotion through di...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Adv
Autori principali: Wisniewski, Emily O., Mistriotis, Panagiotis, Bera, Kaustav, Law, Robert A., Zhang, Jitao, Nikolic, Milos, Weiger, Michael, Parlani, Maria, Tuntithavornwat, Soontorn, Afthinos, Alexandros, Zhao, Runchen, Wirtz, Denis, Kalab, Petr, Scarcelli, Giuliano, Friedl, Peter, Konstantopoulos, Konstantinos
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2020
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399493/
https://ncbi.nlm.nih.gov/pubmed/32789173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba6505
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